Macrophages

Single-Cell Features of Glioblastoma Macrophages Reveal MARCO as a Stroma-Related Tumor Marker

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Single-Cell Features of Glioblastoma Macrophages Reveal MARCO as a Stroma-Related Tumor Marker

Click the blue text Follow us /Abstract/ Background Macrophages are the most common infiltrating immune cells in gliomas, exhibiting various pro-tumor and anti-tumor effects. However, the different subpopulations of macrophages and their impact on the tumor microenvironment remain unclear. Methods We combined new and previously published single-cell RNA sequencing data from 66 gliomas, analyzing 19,331 … Read more

Fundamental Biology of Macrophages: From Origin to Function

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Fundamental Biology of Macrophages: From Origin to Function

From clicking the blue text above ↑↑↑——“Stem Cell Talk“, mark with a star to follow this popular science account. Life Philosophy Stem Cell Talk Neither praise nor blame To state the facts Is the way of popular science Main Text There is still a long way to go from basic research to clinical application, but … Read more

Macrophage-Specific FGF12 Promotes Liver Fibrosis Progression in Mice

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Macrophage-Specific FGF12 Promotes Liver Fibrosis Progression in Mice

Click the blue text to follow us Liver fibrosis is a common sequel of various chronic liver injuries, characterized by the excessive accumulation of extracellular matrix (ECM) proteins such as type I collagen and fibronectin. The persistence of the fibrotic process often leads to cirrhosis and hepatocellular carcinoma (HCC). The hallmark of liver fibrosis is … Read more