Inflammatory bowel disease (IBD) is a chronic non-specific inflammatory disease that occurs in the gastrointestinal tract and is characterized by recurrent episodes. Its causes and mechanisms remain unclear and may be related to abnormalities in both innate and acquired immune responses within the mucosal tissue, damage to the intestinal mucosal barrier, genetic susceptibility, imbalance of … Read more
Click the blue text Follow us /Abstract/ Background Macrophages are the most common infiltrating immune cells in gliomas, exhibiting various pro-tumor and anti-tumor effects. However, the different subpopulations of macrophages and their impact on the tumor microenvironment remain unclear. Methods We combined new and previously published single-cell RNA sequencing data from 66 gliomas, analyzing 19,331 … Read more
From clicking the blue text above ↑↑↑——“Stem Cell Talk“, mark with a star to follow this popular science account. Life Philosophy Stem Cell Talk Neither praise nor blame To state the facts Is the way of popular science Main Text There is still a long way to go from basic research to clinical application, but … Read more
Click the blue text to follow us Liver fibrosis is a common sequel of various chronic liver injuries, characterized by the excessive accumulation of extracellular matrix (ECM) proteins such as type I collagen and fibronectin. The persistence of the fibrotic process often leads to cirrhosis and hepatocellular carcinoma (HCC). The hallmark of liver fibrosis is … Read more