MDSC: The Tumor’s Chaotic Collective

MDSC: The Tumor's Chaotic Collective

Hi, everyone! I am Xiao Q~ The tumor microenvironment is a battlefield filled with smoke, where various immune cells are the main characters. Although different immune cells look different and exhibit their own abilities, they all share a common ancestor: hematopoietic stem cells (HSC). In a healthy body, HSCs differentiate through four stages into different … Read more

Fundamental Biology of Macrophages: From Origin to Function

Fundamental Biology of Macrophages: From Origin to Function

From clicking the blue text above ↑↑↑——“Stem Cell Talk“, mark with a star to follow this popular science account. Life Philosophy Stem Cell Talk Neither praise nor blame To state the facts Is the way of popular science Main Text There is still a long way to go from basic research to clinical application, but … Read more

New Mechanism of DNA Damage-Induced Aging in Hematopoietic Stem Cells

New Mechanism of DNA Damage-Induced Aging in Hematopoietic Stem Cells

Introduction DNA damage promotes hematopoietic stem cell (HSC) aging, but the underlying molecular mechanisms are not fully understood. On April 17, 2024, the team led by Wang Jianwei from the Chinese Academy of Medical Sciences Blood Disease Hospital (Institute of Hematology, Chinese Academy of Medical Sciences), with Dr. He Hanqing as the first author, published … Read more