Hello everyone, I recommend a new article published in Molecular & Cellular Proteomics, with two corresponding authors, Jurgen Cox and Matthias Mann from the Max Planck Institute of Biochemistry. Professor Mann is a leading figure in the field of proteomics, and Jurgen Cox collaborated with him to develop all components of the MaxQuant ecosystem: the … Read more
Jingjie Academic/Selected Diffuse Glioma is the most common primary central nervous system tumor in adults, which can be classified into astrocytoma, oligodendroglioma, and oligoastrocytoma, with a pathological grade of II to IV. Based on mutations in isocitrate dehydrogenase genes (IDH1/2) and the presence of co-deletion of chromosome arms 1p and 19q (1p19q codel), diffuse gliomas … Read more
Jingjie Academic Interpretation Protein acetylation is one of the major post-translational modifications (PTMs), and lysine acetylation can occur in many eukaryotic and bacterial proteins. Nα-acetylation is a common type of post-translational modification in eukaryotes, involved in regulating protein interactions, localization, folding, and degradation. Nα-acetylation is catalyzed by N-terminal acetyltransferases (NAT) and lysine acetyltransferases (KAT), transferring … Read more