Dichotomous Roles of Smooth Muscle Cell-Derived MCP1 in Atherosclerosis Development
Smooth muscle cells (SMCs) in atherosclerotic plaques exhibit various non-classical phenotypes, which may affect plaque stability, leading to the potential for myocardial infarction or stroke. It is currently believed that different SMC phenotypes play either beneficial or detrimental roles in the pathogenesis of atherosclerotic lesions. The classical view that SMCs promote plaque stability has been … Read more