Designing Feature-Controlled Humanoid Antibody Libraries Using GANs

Designing Feature-Controlled Humanoid Antibody Libraries Using GANs

Antibodies are a class of important biotherapeutics, characterized by significant specificity and effectiveness. However, the high cost and long development time of monoclonal antibody therapies pose challenges for antibody treatment. Therapeutic antibodies must respond quickly to pathogens while ensuring safety. Due to the biophysical properties of many antibodies, they tend to aggregate, precipitate, or undergo … Read more

Protein Design Using RoseTTAFold Sequence Space Diffusion

Protein Design Using RoseTTAFold Sequence Space Diffusion

Hello everyone, today I would like to share an article from Nature Biotechnology titled ‘Multistate and functional protein design using RoseTTAFold sequence space diffusion.’ The corresponding author is Professor David Baker from the University of Washington. His research focuses on protein design and related fields. The function of proteins is determined by their sequence and … Read more